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Wnt Signaling Is Required for the Maintenance of Human Limbal Stem/Progenitor Cells In Vitro

PURPOSE: A chemical approach to examine the role of Wnt signaling in maintaining the stemness and/or proliferation of limbal stem/progenitor cells (LSCs). METHODS: LSCs were isolated from human donor eyes and cultured as single cells for 12 to 14 days with the following small molecules: IIIC3, an an...

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Detalles Bibliográficos
Autores principales: González, Sheyla, Oh, Denise, Baclagon, Elfren R., Zheng, Jie J., Deng, Sophie X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333110/
https://www.ncbi.nlm.nih.gov/pubmed/30640975
http://dx.doi.org/10.1167/iovs.18-25740