A functional interplay between intein and extein sequences in protein splicing compensates for the essential block B histidine

Inteins remove themselves from a precursor protein by protein splicing. Due to the concomitant structural changes of the host protein, this self-processing reaction has enabled many applications in protein biotechnology and chemical biology. We show that the evolved M86 mutant of the Ssp DnaB intein...

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Detalles Bibliográficos
Autores principales: Friedel, Kristina, Popp, Monika A., Matern, Julian C. J., Gazdag, Emerich M., Thiel, Ilka V., Volkmann, Gerrit, Blankenfeldt, Wulf, Mootz, Henning D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333167/
https://www.ncbi.nlm.nih.gov/pubmed/30713635
http://dx.doi.org/10.1039/c8sc01074a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333167/
https://www.ncbi.nlm.nih.gov/pubmed/30713635
http://dx.doi.org/10.1039/c8sc01074a

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