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How to design an optimal sensor network for the unfolded protein response

Cellular protein homeostasis requires continuous monitoring of stress in the endoplasmic reticulum (ER). Stress-detection networks control protein homeostasis by mitigating the deleterious effects of protein accumulation, such as aggregation and misfolding, with precise modulation of chaperone produ...

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Detalles Bibliográficos
Autores principales: Stroberg, Wylie, Aktin, Hadar, Savir, Yonatan, Schnell, Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333173/
https://www.ncbi.nlm.nih.gov/pubmed/30256705
http://dx.doi.org/10.1091/mbc.E18-01-0060