Depletion of SMC5/6 sensitizes male germ cells to DNA damage

The structural maintenance of chromosomes complex SMC5/6 is thought to be essential for DNA repair and chromosome segregation during mitosis and meiosis. To determine the requirements of the SMC5/6 complex during mouse spermatogenesis we combined a conditional knockout allele for Smc5, with four ger...

Descripción completa

Detalles Bibliográficos
Autores principales: Hwang, G., Verver, D. E., Handel, M. A., Hamer, G., Jordan, P. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333175/
https://www.ncbi.nlm.nih.gov/pubmed/30281394
http://dx.doi.org/10.1091/mbc.E18-07-0459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333175/
https://www.ncbi.nlm.nih.gov/pubmed/30281394
http://dx.doi.org/10.1091/mbc.E18-07-0459

Ejemplares similares