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Depletion of SMC5/6 sensitizes male germ cells to DNA damage

The structural maintenance of chromosomes complex SMC5/6 is thought to be essential for DNA repair and chromosome segregation during mitosis and meiosis. To determine the requirements of the SMC5/6 complex during mouse spermatogenesis we combined a conditional knockout allele for Smc5, with four ger...

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Detalles Bibliográficos
Autores principales:	Hwang, G., Verver, D. E., Handel, M. A., Hamer, G., Jordan, P. W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333175/ https://www.ncbi.nlm.nih.gov/pubmed/30281394 http://dx.doi.org/10.1091/mbc.E18-07-0459

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