Compressive force induces reversible chromatin condensation and cell geometry–dependent transcriptional response

Fibroblasts exhibit heterogeneous cell geometries in tissues and integrate both mechanical and biochemical signals in their local microenvironment to regulate genomic programs via chromatin remodelling. While in connective tissues fibroblasts experience tensile and compressive forces (CFs), the role...

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Detalles Bibliográficos
Autores principales: Damodaran, Karthik, Venkatachalapathy, Saradha, Alisafaei, Farid, Radhakrishnan, A. V., Sharma Jokhun, Doorgesh, Shenoy, Vivek B., Shivashankar, G. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333178/
https://www.ncbi.nlm.nih.gov/pubmed/30256731
http://dx.doi.org/10.1091/mbc.E18-04-0256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333178/
https://www.ncbi.nlm.nih.gov/pubmed/30256731
http://dx.doi.org/10.1091/mbc.E18-04-0256

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