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Compressive force induces reversible chromatin condensation and cell geometry–dependent transcriptional response
Fibroblasts exhibit heterogeneous cell geometries in tissues and integrate both mechanical and biochemical signals in their local microenvironment to regulate genomic programs via chromatin remodelling. While in connective tissues fibroblasts experience tensile and compressive forces (CFs), the role...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333178/ https://www.ncbi.nlm.nih.gov/pubmed/30256731 http://dx.doi.org/10.1091/mbc.E18-04-0256 |