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A new biomimetic assay reveals the temporal role of matrix stiffening in cancer cell invasion
Tumor initiation and growth is associated with significant changes in the surrounding tissue. During carcinoma progression, a global stiffening of the extracellular matrix is observed and is interpreted as a signature of aggressive invasive tumors. However, it is still unknown whether this increase...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333180/ https://www.ncbi.nlm.nih.gov/pubmed/30303750 http://dx.doi.org/10.1091/mbc.E18-01-0068 |