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The biosynthetic implications of late-stage condensation domain selectivity during glycopeptide antibiotic biosynthesis

Non-ribosomal peptide synthesis is a highly important biosynthetic pathway for the formation of many secondary metabolites of medical relevance. Due to the challenges associated with the chemical synthesis of many of the products of these assembly lines, understanding the activity and selectivity of...

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Detalles Bibliográficos
Autores principales: Schoppet, Melanie, Peschke, Madeleine, Kirchberg, Anja, Wiebach, Vincent, Süssmuth, Roderich D., Stegmann, Evi, Cryle, Max J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333238/
https://www.ncbi.nlm.nih.gov/pubmed/30713624
http://dx.doi.org/10.1039/c8sc03530j