Racemic vs. enantiopure inert Ti(iv) complex of a single diaminotetrakis(phenolato) ligand in anticancer activity toward human drug-sensitive and -resistant cancer cell lines

A tetrakis(phenolato) Ti(iv) complex was synthesized in racemic and optically pure form, exhibiting high hydrolytic stability, and similar cytotoxicity for all stereochemical forms on HT-29 and A2780 cancer cells. Higher activity of the racemate on drug-resistant A2780cp and A2780adr lines implies a...

Descripción completa

Detalles Bibliográficos
Autores principales: Miller, Maya, Tshuva, Edit Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333245/
https://www.ncbi.nlm.nih.gov/pubmed/30713687
http://dx.doi.org/10.1039/c8ra08925f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333245/
https://www.ncbi.nlm.nih.gov/pubmed/30713687
http://dx.doi.org/10.1039/c8ra08925f

Ejemplares similares