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Crystal structure of Mycobacterium tuberculosis FadB2 implicated in mycobacterial β-oxidation

The intracellular pathogen Mycobacterium tuberculosis is the causative agent of tuberculosis, which is a leading cause of mortality worldwide. The survival of M. tuberculosis in host macrophages through long-lasting periods of persistence depends, in part, on breaking down host cell lipids as a carb...

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Detalles Bibliográficos
Autores principales: Cox, Jonathan A. G., Taylor, Rebecca C., Brown, Alistair K., Attoe, Samuel, Besra, Gurdyal S., Fütterer, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333283/
https://www.ncbi.nlm.nih.gov/pubmed/30644849
http://dx.doi.org/10.1107/S2059798318017242