Cargando…
Crystal structure of Mycobacterium tuberculosis FadB2 implicated in mycobacterial β-oxidation
The intracellular pathogen Mycobacterium tuberculosis is the causative agent of tuberculosis, which is a leading cause of mortality worldwide. The survival of M. tuberculosis in host macrophages through long-lasting periods of persistence depends, in part, on breaking down host cell lipids as a carb...
Autores principales: | Cox, Jonathan A. G., Taylor, Rebecca C., Brown, Alistair K., Attoe, Samuel, Besra, Gurdyal S., Fütterer, Klaus |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333283/ https://www.ncbi.nlm.nih.gov/pubmed/30644849 http://dx.doi.org/10.1107/S2059798318017242 |
Ejemplares similares
-
Platensimycin Activity against Mycobacterial β-Ketoacyl-ACP Synthases
por: Brown, Alistair K., et al.
Publicado: (2009) -
A Persistent Tuberculosis Outbreak in the UK Is Characterized by Hydrophobic fadB4-Deficient Mycobacterium tuberculosis That Replicates Rapidly in Macrophages
por: Farzand, Robeena, et al.
Publicado: (2022) -
The Mycobacterium tuberculosis β-oxidation genes echA5 and fadB3 are dispensable for growth in vitro and in vivo
por: Williams, Kerstin J., et al.
Publicado: (2011) -
Structural and functional analysis of the solute-binding protein UspC from Mycobacterium tuberculosis that is specific for amino sugars
por: Fullam, Elizabeth, et al.
Publicado: (2016) -
Dimerization of inositol monophosphatase Mycobacterium tuberculosis SuhB is not constitutive, but induced by binding of the activator Mg(2+)
por: Brown, Alistair K, et al.
Publicado: (2007)