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Computational characterization of the peptidome in transporter associated with antigen processing (TAP)-deficient cells
The transporter associated with antigen processing (TAP) is a key element of the major histocompatibility complex (MHC) class I antigen processing and presentation pathway. Nonfunctional TAP complexes impair the translocation of cytosol-derived proteolytic peptides to the endoplasmic reticulum lumen...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333353/ https://www.ncbi.nlm.nih.gov/pubmed/30645615 http://dx.doi.org/10.1371/journal.pone.0210583 |