Advancing multimer analysis of von Willebrand factor by single-molecule AFM imaging

The formation of hemostatic plugs at sites of vascular injury crucially involves the multimeric glycoprotein von Willebrand factor (VWF). VWF multimers are linear chains of N-terminally linked dimers. The latter are formed from monomers via formation of the C-terminal disulfide bonds Cys2771-Cys2773...

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Detalles Bibliográficos
Autores principales: Löf, Achim, König, Gesa, Schneppenheim, Sonja, Schneppenheim, Reinhard, Benoit, Martin, Budde, Ulrich, Müller, Jochen P., Brehm, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333368/
https://www.ncbi.nlm.nih.gov/pubmed/30645640
http://dx.doi.org/10.1371/journal.pone.0210963

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333368/
https://www.ncbi.nlm.nih.gov/pubmed/30645640
http://dx.doi.org/10.1371/journal.pone.0210963

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