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Rationally designing antisense therapy to keep up with evolving bacterial resistance
Antisense molecules used as antibiotics offer the potential to keep up with acquired resistance, by redesigning the sequence of an antisense. Once bacteria acquire resistance by mutating the targeted sequence, new antisense can readily be designed by using sequence information of a target gene. Howe...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333403/ https://www.ncbi.nlm.nih.gov/pubmed/30645595 http://dx.doi.org/10.1371/journal.pone.0209894 |