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Deep learning identifies genome-wide DNA binding sites of long noncoding RNAs

Long noncoding RNAs (lncRNAs) can exert their function by interacting with the DNA via triplex structure formation. Even though this has been validated with a handful of experiments, a genome-wide analysis of lncRNA-DNA binding is needed. In this paper, we develop and interpret deep learning models...

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Detalles Bibliográficos
Autores principales: Wang, Fan, Chainani, Pranik, White, Tommy, Yang, Jin, Liu, Yu, Soibam, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333433/
https://www.ncbi.nlm.nih.gov/pubmed/30486737
http://dx.doi.org/10.1080/15476286.2018.1551704