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Mouse Cre-LoxP system: general principles to determine tissue-specific roles of target genes

Genetically engineered mouse models are commonly preferred for studying the human disease due to genetic and pathophysiological similarities between mice and humans. In particular, Cre-loxP system is widely used as an integral experimental tool for generating the conditional. This system has enabled...

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Detalles Bibliográficos
Autores principales: Kim, Hyeonhui, Kim, Minki, Im, Sun-Kyoung, Fang, Sungsoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association for Laboratory Animal Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333611/
https://www.ncbi.nlm.nih.gov/pubmed/30671100
http://dx.doi.org/10.5625/lar.2018.34.4.147