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Deregulation and Targeting of TP53 Pathway in Multiple Myeloma

Multiple Myeloma (MM) is an incurable disease characterized by a clonal evolution across the course of the diseases and multiple lines of treatment. Among genomic drivers of the disease, alterations of the tumor suppressor TP53 are associated with poor outcomes. In physiological situation, once acti...

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Detalles Bibliográficos
Autores principales: Jovanović, Katarina K., Escure, Guillaume, Demonchy, Jordane, Willaume, Alexandre, Van de Wyngaert, Zoe, Farhat, Meryem, Chauvet, Paul, Facon, Thierry, Quesnel, Bruno, Manier, Salomon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333636/
https://www.ncbi.nlm.nih.gov/pubmed/30687640
http://dx.doi.org/10.3389/fonc.2018.00665