Zolpidem Activation of Alpha 1-Containing GABA(A) Receptors Selectively Inhibits High Frequency Action Potential Firing of Cortical Neurons

Introduction: High frequency neuronal activity in the cerebral cortex can be induced by noxious stimulation during surgery, brain injury or poisoning. In this scenario, it is essential to block cortical hyperactivity to protect the brain against damage, e.g., by using drugs that act as positive allo...

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Detalles Bibliográficos
Autores principales: Neumann, Elena, Rudolph, Uwe, Knutson, Daniel E., Li, Guanguan, Cook, James M., Hentschke, Harald, Antkowiak, Bernd, Drexler, Berthold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333667/
https://www.ncbi.nlm.nih.gov/pubmed/30687091
http://dx.doi.org/10.3389/fphar.2018.01523

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333667/
https://www.ncbi.nlm.nih.gov/pubmed/30687091
http://dx.doi.org/10.3389/fphar.2018.01523

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