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Zolpidem Activation of Alpha 1-Containing GABA(A) Receptors Selectively Inhibits High Frequency Action Potential Firing of Cortical Neurons
Introduction: High frequency neuronal activity in the cerebral cortex can be induced by noxious stimulation during surgery, brain injury or poisoning. In this scenario, it is essential to block cortical hyperactivity to protect the brain against damage, e.g., by using drugs that act as positive allo...
Autores principales: | Neumann, Elena, Rudolph, Uwe, Knutson, Daniel E., Li, Guanguan, Cook, James M., Hentschke, Harald, Antkowiak, Bernd, Drexler, Berthold |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333667/ https://www.ncbi.nlm.nih.gov/pubmed/30687091 http://dx.doi.org/10.3389/fphar.2018.01523 |
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