Impaired Nuclear Export of Polyglutamine-Expanded Androgen Receptor in Spinal and Bulbar Muscular Atrophy

Spinal and bulbar muscular atrophy (SBMA) is a neuromuscular disease caused by polyglutamine (polyQ) expansion in the androgen receptor (AR). Prior studies have highlighted the importance of AR nuclear localization in SBMA pathogenesis; therefore, in this study, we sought to determine the role of AR...

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Detalles Bibliográficos
Autores principales: Arnold, Frederick J., Pluciennik, Anna, Merry, Diane E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333819/
https://www.ncbi.nlm.nih.gov/pubmed/30644418
http://dx.doi.org/10.1038/s41598-018-36784-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333819/
https://www.ncbi.nlm.nih.gov/pubmed/30644418
http://dx.doi.org/10.1038/s41598-018-36784-4

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