Activation of c-Met in cancer cells mediates growth-promoting signals against oxidative stress through Nrf2-HO-1

Any imbalance between reactive oxygen species (ROS) generation and the anti-oxidant capacity lead to cellular oxidative stress. Many chemotherapeutic agents mediate their cytotoxic functions through the generation of ROS. c-Met, a receptor tyrosine kinase, is over-expressed in renal cancer and plays...

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Detalles Bibliográficos
Autores principales: Chakraborty, Samik, Balan, Murugabaskar, Flynn, Evelyn, Zurakowski, David, Choueiri, Toni K., Pal, Soumitro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333845/
https://www.ncbi.nlm.nih.gov/pubmed/30647407
http://dx.doi.org/10.1038/s41389-018-0116-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333845/
https://www.ncbi.nlm.nih.gov/pubmed/30647407
http://dx.doi.org/10.1038/s41389-018-0116-9

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