Late Endosomes Act as mRNA Translation Platforms and Sustain Mitochondria in Axons

Local translation regulates the axonal proteome, playing an important role in neuronal wiring and axon maintenance. How axonal mRNAs are localized to specific subcellular sites for translation, however, is not understood. Here we report that RNA granules associate with endosomes along the axons of r...

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Detalles Bibliográficos
Autores principales: Cioni, Jean-Michel, Lin, Julie Qiaojin, Holtermann, Anne V., Koppers, Max, Jakobs, Maximilian A.H., Azizi, Afnan, Turner-Bridger, Benita, Shigeoka, Toshiaki, Franze, Kristian, Harris, William A., Holt, Christine E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333918/
https://www.ncbi.nlm.nih.gov/pubmed/30612743
http://dx.doi.org/10.1016/j.cell.2018.11.030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333918/
https://www.ncbi.nlm.nih.gov/pubmed/30612743
http://dx.doi.org/10.1016/j.cell.2018.11.030

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