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Diagnostic Significance of p38 Isoforms (p38α, p38β, p38γ, p38δ) in Head and Neck Squamous Cell Carcinoma: Comparative Serum Level Evaluation and Design of Novel Peptide Inhibitor Targeting the Same

PURPOSE: The p38 mitogen-activated protein kinase (MAPKs) play a crucial role in the production of pro-inflammatory cytokines and over-expression of it increase cytokines which promote cancer. Among four isoforms, p38α has been well studied in head and neck squamous cell carcinoma (HNSCC) and other...

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Detalles Bibliográficos
Autores principales: Sahu, Vishal, Nigam, Lokesh, Agnihotri, Vertica, Gupta, Abhishek, Shekhar, Shashank, Subbarao, Naidu, Bhaskar, Suman, Dey, Sharmistha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333999/
https://www.ncbi.nlm.nih.gov/pubmed/29747487
http://dx.doi.org/10.4143/crt.2018.105