Cargando…

The use of a surface active agent in the protection of a fusion protein during bioprocessing

The bioprocessing of a fusion protein is characterised by low yields and at a series of recovery and purification stages that leads to an overall 90% loss. Much of this apparent loss is due to the denaturation of a protein, missing a vital affinity ligand. However, there is evidence of the protectio...

Descripción completa

Detalles Bibliográficos
Autores principales: Blas, Peter, Tolner, Berend, Ward, John, Chester, Kerry, Hoare, Mike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334174/
https://www.ncbi.nlm.nih.gov/pubmed/30102764
http://dx.doi.org/10.1002/bit.26817