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Crosstalk of Genetic Variants, Allele-Specific DNA Methylation, and Environmental Factors for Complex Disease Risk

Over the past decades, genome-wide association studies (GWAS) have identified thousands of phenotype-associated DNA sequence variants for potential explanations of inter-individual phenotypic differences and disease susceptibility. However, it remains a challenge for translating the associations int...

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Detalles Bibliográficos
Autores principales: Wang, Huishan, Lou, Dan, Wang, Zhibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334214/
https://www.ncbi.nlm.nih.gov/pubmed/30687383
http://dx.doi.org/10.3389/fgene.2018.00695