A Meiotic Checkpoint Alters Repair Partner Bias to Permit Inter-sister Repair of Persistent DSBs

Accurate meiotic chromosome segregation critically depends on the formation of inter-homolog crossovers initiated by double-strand breaks (DSBs). Inaccuracies in this process can drive aneuploidy and developmental defects, but how meiotic cells are protected from unscheduled DNA breaks remains unexp...

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Detalles Bibliográficos
Autores principales: Garcia-Muse, Tatiana, Galindo-Diaz, U., Garcia-Rubio, M., Martin, J.S., Polanowska, J., O’Reilly, N., Aguilera, A., Boulton, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334227/
https://www.ncbi.nlm.nih.gov/pubmed/30650366
http://dx.doi.org/10.1016/j.celrep.2018.12.074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334227/
https://www.ncbi.nlm.nih.gov/pubmed/30650366
http://dx.doi.org/10.1016/j.celrep.2018.12.074

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