BM-MSC-derived exosomes alleviate radiation-induced bone loss by restoring the function of recipient BM-MSCs and activating Wnt/β-catenin signaling

BACKGROUND: Radiotherapy to cancer patients is inevitably accompanied by normal tissue injury, and the bone is one of the most commonly damaged tissues. Damage to bone marrow mesenchymal stem cells (BM-MSCs) induced by radiation is thought to be a major cause of radiation-induced bone loss. Exosomes...

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Detalles Bibliográficos
Autores principales: Zuo, Rui, Liu, Minghan, Wang, Yanqiu, Li, Jie, Wang, Wenkai, Wu, Junlong, Sun, Chao, Li, Bin, Wang, Ziwen, Lan, Weiren, Zhang, Chao, Shi, Chunmeng, Zhou, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334443/
https://www.ncbi.nlm.nih.gov/pubmed/30646958
http://dx.doi.org/10.1186/s13287-018-1121-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334443/
https://www.ncbi.nlm.nih.gov/pubmed/30646958
http://dx.doi.org/10.1186/s13287-018-1121-9

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