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BM-MSC-derived exosomes alleviate radiation-induced bone loss by restoring the function of recipient BM-MSCs and activating Wnt/β-catenin signaling

BACKGROUND: Radiotherapy to cancer patients is inevitably accompanied by normal tissue injury, and the bone is one of the most commonly damaged tissues. Damage to bone marrow mesenchymal stem cells (BM-MSCs) induced by radiation is thought to be a major cause of radiation-induced bone loss. Exosomes...

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Detalles Bibliográficos
Autores principales:	Zuo, Rui, Liu, Minghan, Wang, Yanqiu, Li, Jie, Wang, Wenkai, Wu, Junlong, Sun, Chao, Li, Bin, Wang, Ziwen, Lan, Weiren, Zhang, Chao, Shi, Chunmeng, Zhou, Yue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334443/ https://www.ncbi.nlm.nih.gov/pubmed/30646958 http://dx.doi.org/10.1186/s13287-018-1121-9

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