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Sequential trafficking of Env and Gag to HIV-1 T cell virological synapses revealed by live imaging

BACKGROUND: HIV infection is enhanced by cell adhesions that form between infected and uninfected T cells called virological synapses (VS). VS are initiated by an interaction between Env and CD4 on cell surfaces and result in the recruitment of virus assembly to the site of cell–cell contact. Howeve...

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Detalles Bibliográficos
Autores principales: Wang, Lili, Izadmehr, Sudeh, Kamau, Edwin, Kong, Xiang-Peng, Chen, Benjamin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334456/
https://www.ncbi.nlm.nih.gov/pubmed/30646921
http://dx.doi.org/10.1186/s12977-019-0464-3