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Sequential trafficking of Env and Gag to HIV-1 T cell virological synapses revealed by live imaging
BACKGROUND: HIV infection is enhanced by cell adhesions that form between infected and uninfected T cells called virological synapses (VS). VS are initiated by an interaction between Env and CD4 on cell surfaces and result in the recruitment of virus assembly to the site of cell–cell contact. Howeve...
Autores principales: | Wang, Lili, Izadmehr, Sudeh, Kamau, Edwin, Kong, Xiang-Peng, Chen, Benjamin K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334456/ https://www.ncbi.nlm.nih.gov/pubmed/30646921 http://dx.doi.org/10.1186/s12977-019-0464-3 |
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