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Overexpression of CCDC69 activates p14(ARF)/MDM2/p53 pathway and confers cisplatin sensitivity

OBJECTIVES: The aim of the study is to explore the relationship between CCDC69 expression and resistance of ovarian cancer cells to cisplatin and reveal the underlying mechanism. METHODS: One hundred thirty five ovarian cancer patients with intact chemo-response information from The Cancer Genome At...

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Detalles Bibliográficos
Autores principales: Cui, Long, Zhou, Fang, Chen, Cui, Wang, Chi Chiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334460/
https://www.ncbi.nlm.nih.gov/pubmed/30651135
http://dx.doi.org/10.1186/s13048-019-0479-3