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Hemopexin alleviates cognitive dysfunction after focal cerebral ischemia-reperfusion injury in rats

BACKGROUND: Ischemia-reperfusion (I/R) is a critical pathophysiological basis of cognitive dysfunction caused by ischemia stroke. Heme-oxygenase-1 (HO-1) is the rate-limiting enzyme for the elimination of excessive free heme by combining with hemopexin (HPX), a plasma protein that contributes to eli...

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Detalles Bibliográficos
Autores principales: Dong, Beibei, Yang, Yongyan, Zhang, Zhishen, Xie, Keliang, Su, Lin, Yu, Yonghao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334464/
https://www.ncbi.nlm.nih.gov/pubmed/30646866
http://dx.doi.org/10.1186/s12871-019-0681-2