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Hemopexin alleviates cognitive dysfunction after focal cerebral ischemia-reperfusion injury in rats
BACKGROUND: Ischemia-reperfusion (I/R) is a critical pathophysiological basis of cognitive dysfunction caused by ischemia stroke. Heme-oxygenase-1 (HO-1) is the rate-limiting enzyme for the elimination of excessive free heme by combining with hemopexin (HPX), a plasma protein that contributes to eli...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334464/ https://www.ncbi.nlm.nih.gov/pubmed/30646866 http://dx.doi.org/10.1186/s12871-019-0681-2 |