Cargando…

Biochemical characterization of the minimal domains of an iterative eukaryotic polyketide synthase

Iterative type I polyketide synthases (PKS) are megaenzymes essential to the biosynthesis of an enormously diverse array of bioactive natural products. Each PKS contains minimally three functional domains, β‐ketosynthase (KS), acyltransferase (AT), and acyl carrier protein (ACP), and a subset of red...

Descripción completa

Detalles Bibliográficos
Autores principales: Sabatini, Martin, Comba, Santiago, Altabe, Silvia, Recio‐Balsells, Alejandro I., Labadie, Guillermo R., Takano, Eriko, Gramajo, Hugo, Arabolaza, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334511/
https://www.ncbi.nlm.nih.gov/pubmed/30300504
http://dx.doi.org/10.1111/febs.14675