Histone Acetyltransferase KAT2A Stabilizes Pluripotency with Control of Transcriptional Heterogeneity

Cell fate transitions in mammalian stem cell systems have often been associated with transcriptional heterogeneity; however, existing data have failed to establish a functional or mechanistic link between the two phenomena. Experiments in unicellular organisms support the notion that transcriptional...

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Detalles Bibliográficos
Autores principales: Moris, Naomi, Edri, Shlomit, Seyres, Denis, Kulkarni, Rashmi, Domingues, Ana Filipa, Balayo, Tina, Frontini, Mattia, Pina, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334525/
https://www.ncbi.nlm.nih.gov/pubmed/30270482
http://dx.doi.org/10.1002/stem.2919