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PDCD4 Knockdown Induces Senescence in Hepatoma Cells by Up-Regulating the p21 Expression

While the over-expression of tumor suppressor programmed cell death 4 (PDCD4) induces apoptosis, it was recently shown that PDCD4 knockdown also induced apoptosis. In this study, we examined the cell cycle regulators whose activation is affected by PDCD4 knockdown to investigate the contribution of...

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Detalles Bibliográficos
Autores principales: Guo, Jing, Ozaki, Iwata, Xia, Jinghe, Kuwashiro, Takuya, Kojima, Motoyasu, Takahashi, Hirokazu, Ashida, Kenji, Anzai, Keizo, Matsuhashi, Sachiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334536/
https://www.ncbi.nlm.nih.gov/pubmed/30687637
http://dx.doi.org/10.3389/fonc.2018.00661