Plasmid-based generation of neural cells from human fibroblasts using non-integrating episomal vectors

Differentiation of human fibroblasts into functional neurons depends on the introduction of viral-mediated transcription factors, which present risks of viral gene integration and tumorigenicity. In recent years, although some studies have been successful in directly inducing neurons through sustain...

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Detalles Bibliográficos
Autores principales: Dai, Shao-Bing, Shen, Ting, Zheng, Ting-Ting, Pu, Jia-Li, Chen, Xin-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334614/
https://www.ncbi.nlm.nih.gov/pubmed/30539819
http://dx.doi.org/10.4103/1673-5374.245476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334614/
https://www.ncbi.nlm.nih.gov/pubmed/30539819
http://dx.doi.org/10.4103/1673-5374.245476

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