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Plasmid-based generation of neural cells from human fibroblasts using non-integrating episomal vectors
Differentiation of human fibroblasts into functional neurons depends on the introduction of viral-mediated transcription factors, which present risks of viral gene integration and tumorigenicity. In recent years, although some studies have been successful in directly inducing neurons through sustain...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Medknow Publications & Media Pvt Ltd
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334614/ https://www.ncbi.nlm.nih.gov/pubmed/30539819 http://dx.doi.org/10.4103/1673-5374.245476 |