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Soman‐induced status epilepticus, epileptogenesis, and neuropathology in carboxylesterase knockout mice treated with midazolam

OBJECTIVE: Exposure to chemical warfare nerve agents (CWNAs), such as soman (GD), can induce status epilepticus (SE) that becomes refractory to benzodiazepines when treatment is delayed, leading to increased risk of epileptogenesis, severe neuropathology, and long‐term behavioral and cognitive defic...

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Detalles Bibliográficos
Autores principales: Marrero‐Rosado, Brenda, de Araujo Furtado, Marcio, Schultz, Caroline R., Stone, Michael, Kundrick, Erica, Walker, Katie, O’Brien, Sean, Du, Fu, Lumley, Lucille A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334636/
https://www.ncbi.nlm.nih.gov/pubmed/30368799
http://dx.doi.org/10.1111/epi.14582