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Modulatory Effects of Fingolimod (FTY720) on the Expression of Sphingolipid Metabolism-Related Genes in an Animal Model of Alzheimer’s Disease

Sphingolipid signaling disturbances correlate with Alzheimer’s disease (AD) progression. We examined the influence of FTY720/fingolimod, a sphingosine analog and sphingosine-1-phosphate (S1P) receptor modulator, on the expression of sphingolipid metabolism and signaling genes in a mouse transgenic A...

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Detalles Bibliográficos
Autores principales: Jęśko, Henryk, Wencel, Przemysław L., Lukiw, Walter J., Strosznajder, Robert P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334734/
https://www.ncbi.nlm.nih.gov/pubmed/29687345
http://dx.doi.org/10.1007/s12035-018-1040-x