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A lithium-ion-active aerolysin nanopore for effectively trapping long single-stranded DNA

Wild-type aerolysin (AeL) nanopores allow direct single nucleotide discrimination of very short oligonucleotides (≤10 nt) without labelling, which shows great potential for DNA sensing. To achieve real applications, one major obstacle of AeL is its poor capture ability of long single-stranded DNA (s...

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Detalles Bibliográficos
Autores principales: Hu, Zheng-Li, Li, Meng-Yin, Liu, Shao-Chuang, Ying, Yi-Lun, Long, Yi-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334748/
https://www.ncbi.nlm.nih.gov/pubmed/30746084
http://dx.doi.org/10.1039/c8sc03927e