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Changes in mutation frequency of eight Mendelian inherited disorders in eight pedigree dog populations following introduction of a commercial DNA test

INTRODUCTION: DNA testing for autosomal recessive disease mutations in many dog breeds is now relatively commonplace. There have, however, been few efforts made to determine changes in the frequency of disease causing mutations as a result of probable selection based on the results of DNA testing. T...

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Detalles Bibliográficos
Autores principales: Lewis, T. W., Mellersh, C. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334900/
https://www.ncbi.nlm.nih.gov/pubmed/30650096
http://dx.doi.org/10.1371/journal.pone.0209864