Identification and functional characterization of CD8(+) T regulatory cells in type 1 diabetes patients

Type 1 diabetes is an autoimmune disease where autoreactive T lymphocytes destroy pancreatic beta cells. We previously reported a defect in CD4(+) Tregs cell proliferation and reduced CD4(+) Tregs PD-1 expression in patients. Another ‘memory-like’ regulatory subset, CD8(+) Tregs, evaluated as CD8(+)...

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Detalles Bibliográficos
Autores principales: Pellegrino, Marsha, Crinò, Antonino, Rosado, Manuela M., Fierabracci, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334945/
https://www.ncbi.nlm.nih.gov/pubmed/30650147
http://dx.doi.org/10.1371/journal.pone.0210839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334945/
https://www.ncbi.nlm.nih.gov/pubmed/30650147
http://dx.doi.org/10.1371/journal.pone.0210839

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