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Identification and functional characterization of CD8(+) T regulatory cells in type 1 diabetes patients
Type 1 diabetes is an autoimmune disease where autoreactive T lymphocytes destroy pancreatic beta cells. We previously reported a defect in CD4(+) Tregs cell proliferation and reduced CD4(+) Tregs PD-1 expression in patients. Another ‘memory-like’ regulatory subset, CD8(+) Tregs, evaluated as CD8(+)...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334945/ https://www.ncbi.nlm.nih.gov/pubmed/30650147 http://dx.doi.org/10.1371/journal.pone.0210839 |