Therapeutic Fc fusion protein misfolding: A three-phasic cultivation experimental design

Cell culture process optimization is a critical solution to most of the challenges faced by the pharmaceutical manufacturing. One of the major problems encountered in large-scale production of therapeutic proteins is misfolded protein production. The accumulation of misfolded therapeutic proteins is...

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Detalles Bibliográficos
Autores principales: Ghorbani Aghdam, Atefeh, Moradhaseli, Saeed, Jafari, Farnoush, Motahari, Paria, Samavat, Sepideh, Mahboudi, Rasoul, Maleknia, Shayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334962/
https://www.ncbi.nlm.nih.gov/pubmed/30650123
http://dx.doi.org/10.1371/journal.pone.0210712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334962/
https://www.ncbi.nlm.nih.gov/pubmed/30650123
http://dx.doi.org/10.1371/journal.pone.0210712

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