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Schwann cells, but not Oligodendrocytes, Depend Strictly on Dynamin 2 Function

Myelination requires extensive plasma membrane rearrangements, implying that molecules controlling membrane dynamics play prominent roles. The large GTPase dynamin 2 (DNM2) is a well-known regulator of membrane remodeling, membrane fission, and vesicular trafficking. Here, we genetically ablated Dnm...

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Detalles Bibliográficos
Autores principales: Gerber, Daniel, Ghidinelli, Monica, Tinelli, Elisa, Somandin, Christian, Gerber, Joanne, Pereira, Jorge A, Ommer, Andrea, Figlia, Gianluca, Miehe, Michaela, Nägeli, Lukas G, Suter, Vanessa, Tadini, Valentina, Sidiropoulos, Páris NM, Wessig, Carsten, Toyka, Klaus V, Suter, Ueli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335055/
https://www.ncbi.nlm.nih.gov/pubmed/30648534
http://dx.doi.org/10.7554/eLife.42404