Integrative Analysis of Genome and Expression Profile Data Reveals the Genetic Mechanism of the Diabetic Pathogenesis in Goto Kakizaki (GK) Rats

The Goto Kakizaki (GK) rats which can spontaneously develop type 2 diabetes (T2D), are generated by repeated inbreeding of Wistar rats with glucose intolerance. The glucose intolerance in GK rat is mainly attributed to the impairment in glucose-stimulated insulin secretion (GSIS). In addition, GK ra...

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Detalles Bibliográficos
Autores principales: Meng, Yuhuan, Cui, Ying, Zhang, Wenlu, Fu, Shuying, Huang, Lizhen, Dong, Hua, Du, Hongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335273/
https://www.ncbi.nlm.nih.gov/pubmed/30687391
http://dx.doi.org/10.3389/fgene.2018.00724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335273/
https://www.ncbi.nlm.nih.gov/pubmed/30687391
http://dx.doi.org/10.3389/fgene.2018.00724

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