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Ethyl Pyruvate Stimulates Regulatory T Cells and Ameliorates Type 1 Diabetes Development in Mice

Type 1 diabetes (T1D) is an autoimmune disease in which a strong inflammatory response causes the death of insulin-producing pancreatic β-cells, while inefficient regulatory mechanisms allow that response to become chronic. Ethyl pyruvate (EP), a stable pyruvate derivate and certified inhibitor of a...

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Detalles Bibliográficos
Autores principales: Koprivica, Ivan, Vujičić, Milica, Gajić, Dragica, Saksida, Tamara, Stojanović, Ivana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335294/
https://www.ncbi.nlm.nih.gov/pubmed/30687329
http://dx.doi.org/10.3389/fimmu.2018.03130