Cargando…

Ethyl Pyruvate Stimulates Regulatory T Cells and Ameliorates Type 1 Diabetes Development in Mice

Type 1 diabetes (T1D) is an autoimmune disease in which a strong inflammatory response causes the death of insulin-producing pancreatic β-cells, while inefficient regulatory mechanisms allow that response to become chronic. Ethyl pyruvate (EP), a stable pyruvate derivate and certified inhibitor of a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Koprivica, Ivan, Vujičić, Milica, Gajić, Dragica, Saksida, Tamara, Stojanović, Ivana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335294/ https://www.ncbi.nlm.nih.gov/pubmed/30687329 http://dx.doi.org/10.3389/fimmu.2018.03130

Ejemplares similares

Ethyl Pyruvate Promotes Proliferation of Regulatory T Cells by Increasing Glycolysis
por: Koprivica, Ivan, et al.
Publicado: (2020)

Ethyl Pyruvate Ameliorates Experimental Autoimmune Myocarditis
por: Gajić, Dragica, et al.
Publicado: (2021)

The Role of Macrophage Migration Inhibitory Factor in the Function of Intestinal Barrier
por: Vujicic, Milica, et al.
Publicado: (2018)

Ethyl pyruvate, a versatile protector in inflammation and autoimmunity
por: Koprivica, Ivan, et al.
Publicado: (2022)

Development of Type 1 Diabetes in Mice Is Associated with a Decrease in IL-2-Producing ILC3 and FoxP3(+) Treg in the Small Intestine
por: Saksida, Tamara, et al.
Publicado: (2023)

Ethyl Pyruvate Induces Tolerogenic Dendritic Cells
por: Djedovic, Neda, et al.
Publicado: (2019)

ILC3: a case of conflicted identity
por: Koprivica, Ivan, et al.
Publicado: (2023)

Modulation of Intestinal ILC3 for the Treatment of Type 1 Diabetes
por: Stojanović, Ivana, et al.
Publicado: (2021)

Mesenchymal Stem Cells From Mouse Hair Follicles Reduce Hypertrophic Scarring in a Murine Wound Healing Model
por: Li, Hanluo, et al.
Publicado: (2022)

Ethyl Pyruvate Ameliorates The Damage Induced by Cyclophosphamide on Adult Mice Testes
por: Bakhtiary, Zahra, et al.
Publicado: (2016)

Ferroptosis as a Novel Determinant of β-Cell Death in Diabetic Conditions
por: Stancic, Ana, et al.
Publicado: (2022)

Ethyl Pyruvate Modulates Murine Dendritic Cell Activation and Survival Through Their Immunometabolism
por: Chakhtoura, Marita, et al.
Publicado: (2019)

Editorial: Sex differences in immunometabolism, prophylaxis and therapy
por: Fink, Ashley, et al.
Publicado: (2023)

Bench-to-bedside review: Amelioration of acute renal impairment using ethyl pyruvate
por: Reade, Michael C, et al.
Publicado: (2005)

C1QTNF3 is Upregulated During Subcutaneous Adipose Tissue Remodeling and Stimulates Macrophage Chemotaxis and M1-Like Polarization
por: Micallef, Peter, et al.
Publicado: (2022)

Ethyl Pyruvate Ameliorates Hepatic Ischemia-Reperfusion Injury by Inhibiting Intrinsic Pathway of Apoptosis and Autophagy
por: Shen, Miao, et al.
Publicado: (2013)

Protective effects of ethyl pyruvate on sperm quality in cyclophosphamide treated mice
por: Bakhtiary, Zahra, et al.
Publicado: (2015)

Amelioration of Autoimmune Diabetes of NOD Mice by Immunomodulating Probiotics
por: Kim, Tae Kang, et al.
Publicado: (2020)

Corrigendum to “Ethyl Pyruvate Ameliorates Hepatic Ischemia-Reperfusion Injury by Inhibiting Intrinsic Pathway of Apoptosis and Autophagy”
por: Shen, Miao, et al.
Publicado: (2016)

Ethyl pyruvate ameliorate inflammatory response of sinonasal mucosa by inhibiting HMGB1 in rats with acute rhinosinusitis
por: Liang, Xiang, et al.
Publicado: (2021)

Defining the ferroptotic phenotype of beta cells in type 1 diabetes and its inhibition as a potential antidiabetic strategy
por: Markelic, Milica, et al.
Publicado: (2023)

Ethyl Pyruvate Pretreatment Attenuates Concanavalin A-Induced Autoimmune Hepatitis in Mice
por: Shen, Miao, et al.
Publicado: (2014)

Ethyl pyruvate treatment ameliorates pancreatic damage: evidence from a rat model of acute necrotizing pancreatitis
por: Turkyilmaz, Serdar, et al.
Publicado: (2017)

Protective effect of ethyl pyruvate on mice sperm parameters in phenylhydrazine induced hemolytic anemia
por: Mozafari, Ali Akbar, et al.
Publicado: (2016)

Protective effect of ethyl pyruvate on testicular histology and fertilization potential in cyclophosphamide treated mice
por: Bakhtiary, Zahra, et al.
Publicado: (2020)

Esculetin Ameliorates Psoriasis-Like Skin Disease in Mice by Inducing CD4(+)Foxp3(+) Regulatory T Cells
por: Chen, Yuchao, et al.
Publicado: (2018)

Protective effects of ethyl pyruvate in cisplatin-induced nephrotoxicity
por: Kelle, Ilker, et al.
Publicado: (2014)

Impact of ethyl pyruvate on Adriamycin-induced cardiomyopathy in rats
por: Liu, Menglin, et al.
Publicado: (2016)

The anticoagulant effects of ethyl pyruvate in whole blood samples
por: Haidl, Harald, et al.
Publicado: (2020)

Highly Selective Oxidation of Ethyl Lactate to Ethyl Pyruvate Catalyzed by Mesoporous Vanadia–Titania
por: Zhang, Wei, et al.
Publicado: (2018)

Ethyl pyruvate for the treatment of acetaminophen intoxication: alternative to N-acetylcysteine?
por: Wagner, Florian, et al.
Publicado: (2012)

Effect of Ethyl Pyruvate on Paclitaxel-Induced Neuropathic Pain in Rats
por: Choi, Seong Soo, et al.
Publicado: (2013)

Ethyl pyruvate protects against sepsis by regulating energy metabolism
por: Kang, Hongjun, et al.
Publicado: (2016)

Attenuation of Methotrexate-Induced Embryotoxicity and Oxidative Stress by Ethyl Pyruvate
por: Najafi, Gholamreza, et al.
Publicado: (2016)

PSORI-CM02 Formula Increases CD4+ Foxp3+ Regulatory T Cell Frequency and Ameliorates Imiquimod-Induced Psoriasis in Mice
por: Chen, Haiming, et al.
Publicado: (2018)

T Regulatory Cells From Non-obese Diabetic Mice Show Low Responsiveness to IL-2 Stimulation and Exhibit Differential Expression of Anergy-Related and Ubiquitination Factors
por: Godoy, Gloria J., et al.
Publicado: (2019)

Prevention of cataract in diabetic mice by topical pyruvate
por: Hegde, KR, et al.
Publicado: (2011)

Prostaglandin E2 Stimulates the Expansion of Regulatory Hematopoietic Stem and Progenitor Cells in Type 1 Diabetes
por: Ben Nasr, Moufida, et al.
Publicado: (2018)

Lactobacillus sakei WIKIM30 Ameliorates Atopic Dermatitis-Like Skin Lesions by Inducing Regulatory T Cells and Altering Gut Microbiota Structure in Mice
por: Kwon, Min-Sung, et al.
Publicado: (2018)

Corrigendum: PSORI-CM02 Formula Increases CD4+ Foxp3+ Regulatory T Cell Frequency and Ameliorates Imiquimod-Induced Psoriasis in Mice
por: Chen, Haiming, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_2o7s5ojspndbjj89fqokpm7vbc