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Tau and mTOR: The Hotspots for Multifarious Diseases in Alzheimer's Development

The hyperphosphorylation of tau protein and the overexpression of mTOR are considered to be the driving force behind Aβ plaques and Neurofibrillay Tangles (NFT's), hallmarks of Alzheimer's disease (AD). It is now evident that miscellaneous diseases such as Diabetes, Autoimmune diseases, Ca...

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Detalles Bibliográficos
Autores principales: Mueed, Zeba, Tandon, Pallavi, Maurya, Sanjeev Kumar, Deval, Ravi, Kamal, Mohammad A., Poddar, Nitesh Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335350/
https://www.ncbi.nlm.nih.gov/pubmed/30686983
http://dx.doi.org/10.3389/fnins.2018.01017